Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7504485 | Drug and Alcohol Dependence | 2015 | 7 Pages |
Abstract
Varenicline is highly efficacious in decreasing nicotine self-administration either alone or in combination with alcohol. However, varenicline failed to influence both operant responding for alcohol and home-cage alcohol drinking in msP animals. Taken together, our findings suggest that the effects of varenicline could be specific to nicotine under conditions where excessive alcohol drinking is facilitated by genetic factors as in msP rats.
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Authors
Giulia Scuppa, Andrea Cippitelli, Lawrence Toll, Roberto Ciccocioppo, Massimo Ubaldi,