Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7505729 | Drug and Alcohol Dependence | 2014 | 7 Pages |
Abstract
These results demonstrate that-even when sex differences in acute THC potency are controlled-females develop more antinociceptive tolerance to THC than males. Given the importance of drug tolerance in the development of drug dependence, these results suggest that females may be more vulnerable than males to developing dependence after chronic cannabinoid exposure.
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Authors
Alexa A. Wakley, Jenny L. Wiley, Rebecca M. Craft,