| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7505752 | Drug and Alcohol Dependence | 2014 | 8 Pages |
Abstract
The CHRNA5 genetic risk synergized the effect of partner smoking, producing an especially low likelihood of successful smoking reduction in two complementary studies. This suggests that the genetic vulnerability may be mitigated by altering environmental factors. In addition, cessation pharmacotherapy neutralizes the increase in cessation failure associated with combined genetic and environmental risks, which has possible relevance to treatment algorithms.
Keywords
Related Topics
Life Sciences
Neuroscience
Behavioral Neuroscience
Authors
Li-Shiun Chen, Timothy B. Baker, Megan E. Piper, Stevens S. Smith, Charles Gu, Richard A. Grucza, George Davey Smith, Marcus Munafo, Laura J. Bierut,