Hepatotoxicity in a 52-week randomized trial of short-term versus long-term treatment with buprenorphine/naloxone in HIV-negative injection opioid users in China and Thailand

Article ID	Journal	Published Year	Pages	File Type
7505936	Drug and Alcohol Dependence	2014	7 Pages	PDF

Abstract

Over 52-week follow-up, the risk of hepatotoxicity was similar in opioid injectors receiving brief and prolonged treatment with BUP/NX. These data suggest that most hepatotoxic events observed during treatment with BUP/NX are due to other factors.

Keywords

Alanine aminotransferase Injection drug use Safety Buprenorphine/Naloxone Hepatotoxicity Hepatitis C virus opioid dependence HIV prevention

Related Topics

Life Sciences Neuroscience Behavioral Neuroscience

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Hepatotoxicity in a 52-week randomized trial of short-term versus long-term treatment with buprenorphine/naloxone in HIV-negative injection opioid users in China and Thailand

Authors

Gregory M. Lucas, Alicia Young, Deborah Donnell, Paul Richardson, Apinun Aramrattana, Yiming Shao, Yuhua Ruan, Wei Liu, Liping Fu, Jun Ma, David D. Celentano, David Metzger, J. Brooks Jackson, David Burns,