Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7506790 | Drug and Alcohol Dependence | 2014 | 8 Pages |
Abstract
Chronic, ethanol self-administration up-regulates hippocampal 5-HT1A receptor density in a region-specific manner that does not appear to be due to alterations at the level of transcription but instead may be due to increased receptor trafficking. Further exploration of the mechanisms mediating chronic ethanol-induced 5-HT1A receptor up-regulation and how hippocampal neurotransmission is altered is warranted.
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Authors
Elizabeth J. Burnett, Kathleen A. Grant, April T. Davenport, Scott E. Hemby, David P. Friedman,