Article ID Journal Published Year Pages File Type
7506977 Drug and Alcohol Dependence 2014 5 Pages PDF
Abstract
Age related deficits in electrophysiological components such as P20 or event-related gamma may be due to an interruption of normal neural maturation. Reduction of NMDAR signaling during adolescence leads to delayed-onset disruption of gamma oscillations and the P20 component of the ERP. Further, delayed onset of impairment following adolescent ketamine abuse suggests that methods could be developed to detect and treat the early effects of drug exposure prior to the onset of disability.
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Life Sciences Neuroscience Behavioral Neuroscience
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