Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7507845 | Drug and Alcohol Dependence | 2012 | 8 Pages |
Abstract
These results suggest that the GABAB receptor subtype is involved in the abuse-related effects of Î9-THC, and that GABAB receptors were responsible, at least in part, for the effects of tiagabine-induced elevated GABA on cannabinoid-related behaviors in our previous study. Future research should test GABAergic compounds selective for other GABA receptor subtypes (i.e., GABAA) to determine the contribution of the different GABA receptors in the effects of Î9-THC, and by extension cannabis, in humans.
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Authors
Joshua A. Lile, Thomas H. Kelly, Lon R. Hays,