| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7508165 | Drug and Alcohol Dependence | 2012 | 9 Pages |
Abstract
Differences between the short- and long-abstinence groups in the patterns of functional recruitment suggest different cognitive control demands at different stages in abstinence. Short-term abstinence showed increased inhibition-related dorsolateral and inferior frontal activity indicative of the need for increased inhibitory control while long-term abstinence showed increased error-related ACC activity indicative of heightened behavioral monitoring. The results suggest that the integrity of prefrontal systems that underlie cognitive control functions may be an important characteristic of successful long-term abstinence.
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Authors
Colm G. Connolly, John J. Foxe, Jay Nierenberg, Marina Shpaner, Hugh Garavan,