Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
755911 | Communications in Nonlinear Science and Numerical Simulation | 2011 | 8 Pages |
Abstract
This paper presents a very effective numerical method for the solution of the two-compartmental pharmacokinetic model for oral drug administration. This model consists of a set of two fractional order differential equations which connect the two compartments. The first compartment represents the gut while the second compartment corresponds to the drug concentration in the target tissue. For ease of computation, the numerical solution is also created as a Matlab function.
Research highlights► Very effective numerical method for the solution of the two-compartmental model. ► Analysis of a model, which consist of a set of two fractional differential equations. ► Numerical solution of model is created as a Matlab function.
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Authors
Ivo Petráš, Richard L. Magin,