Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization

Article ID	Journal	Published Year	Pages	File Type
7561021	Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics	2013	11 Pages	PDF

Keywords

TGFBI FAS1 TGFBIp DSS SUMO IPTG RMSF RMSD PDB GCD EMI nuclear magnetic resonance 2,2-dimethyl-2-silapentane-5-sulfonate LCD root-mean-square deviation isopropyl β-D-1-thiogalactopyranoside Protein misfolding diseases protein aggregation Proteolytic degradation NMR granular corneal dystrophy Corneal dystrophy lattice corneal dystrophy Molecular dynamics NMR Structure Rdc lysogeny broth root-mean-square fluctuation wild-type Protein Data Bank optical density Residual dipolar couplings small ubiquitin-like modifier

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

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Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization

Authors

Jarl Underhaug, Heidi KoldsÃ¸, Kasper Runager, Jakob Toudahl Nielsen, Charlotte S. SÃ¸rensen, Torsten Kristensen, Daniel E. Otzen, Henrik Karring, Anders Malmendal, Birgit SchiÃ¸tt, Jan J. Enghild, Niels Chr. Nielsen,