| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7561160 | Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics | 2011 | 10 Pages |
Abstract
⺠The oligomer-specific scFv antibodies recognize oligomers of various amyloid. ⺠The scFv inhibited fibrillization and cytotoxicity of various amyloids. ⺠The scFvs disaggregated preformed amyloid fibrils. ⺠The scFvs recognized the amyloid oligomers in the tissues of patients. ⺠Most amyloid fibril deposits were colocalized with oligomers in the tissues.
Keywords
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Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Xi Zhang, Xiao-xia Sun, Di Xue, Dong-ge Liu, Xiao-yan Hu, Min Zhao, Shi-gao Yang, Yang Yang, Yong-jing Xia, Ying Wang, Rui-tian Liu,