Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7564203 | Chinese Journal of Analytical Chemistry | 2017 | 6 Pages |
Abstract
A real-time PCR coupled with invader assay based on template and signal amplification has been established. SRY gene of cell-free fetal DNA in maternal peripheral blood could be detected with high sensitivity, specificity and non-contamination. Through sex determining of fetuses based on SRY gene, risks of sex-linked genetic disorders could be assessed to decrease the birth rate of sick fetuses.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Lin-Lin LIU, Meng-Lin ZHENG, Bing-Jie ZOU, Qin-Xin SONG, Guo-Hua ZHOU,