Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7564420 | Chinese Journal of Analytical Chemistry | 2017 | 8 Pages |
Abstract
A novel HPLC method with on-line gold nanoparticles (AuNPs)-catalyzed luminol chemiluminescence detector was developed for the selective and sensitive determination of levodopa (LD) and carbidopa (CD) with detection limits of 0.89 and 1.08 ng mLâ1, respectively. The validated method was successfully applied to simultaneous quantification of LD and CD in the controlled-release tablets (Sinemet®) and human plasma.
Related Topics
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Authors
Chun-Lei MU, Dong WU, Hai-Feng LU, He XIE, Qun-Lin ZHANG,