| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7564610 | Chinese Journal of Analytical Chemistry | 2017 | 5 Pages |
Abstract
TPP hammerhead ribozymes as the regulatory components for EGFP gene expression is in living mammalian cells. “Switch-off” ribozymes increase pre-mRNA cleavage in the presence of TPP, which results in the decrease of EGFP gene expression. “Switch-on” ribozymes shut off self-cleavage of pre-mRNA upon the external addition of TPP, which leads to the increase of EGFP gene expression.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yuan-Yuan ZHANG, Hui CHENG, Yan SUN, Jin-E WANG, Zheng-Yan WU, Ren-Jun PEI,