Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7583792 | Food Chemistry | 2019 | 5 Pages |
Abstract
Fucoidan is a sulphated polysaccharide, made up mainly of l-fucose, which is found in brown seaweeds. Its chemical structure is diverse and depends on maturity, species and geographical location. The objective of this study was to elucidate the chemical structure of fucoidan from Cladosiphon okamuranus harvested in Japan. The fucoidan was subject to purification prior to monosaccharide profiling, sulphate content determination, and linkage analysis. Our results showed that Japanese Cladosiphon okamuranus fucoidan contained 70.13â¯Â±â¯0.22â¯wt% fucose and 15.16â¯Â±â¯1.17â¯wt% sulphate. Other minor monosaccharides found were d-xylose, d-galactose, d-mannose, d-glucose, d-arabinose, d-rhamnose and d-glucuronic acid. Linkage analysis revealed that fucopyranoside units along the backbone are linked, through α-1,3-glycosidic bonds, with fucose branching at C-2, and one sulphate group at C-4 per every three fucose units, i.e. the structure of fucoidan from Japanese Cladosiphon okamuranus is [â3)-α-fuc(1â]0.52[â3)-α-fuc-4-OSO3-(1â]0.33[â2)-α-fuc]0.14.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Seng Joe Lim, Wan Mustapha Wan Aida, Sonja Schiehser, Thomas Rosenau, Stefan Böhmdorfer,