Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7584872 | Food Chemistry | 2018 | 9 Pages |
Abstract
Zipper-like on/off-switchable and magnetic molecularly imprinted microspheres (SM-MIMs) were constructed using acrylamide (AAm) and 2-acrylamide-2-methyl propanesulfonic acid (AMPS) as functional monomers for 17β-estradiol (17β-E2) recognition and extraction. The imprinted polymer interactions between poly(AAm) (PAAm) and poly(AMPS) (PAMPS) with on/off-switchable property to temperature, exhibited dissociation at relatively higher temperatures (such as 30â¯Â°C) and helped 17β-E2 enter into imprinted sites, leading to higher binding capability. Conversely, the interpolymer complexes between PAAm and PAMPS formed and blocked 17β-E2 access to imprinted sites at lower temperature (such as 20â¯Â°C). SM-MIMs were used as dispersive solid phase extraction (SPE) adsorbent with HPLC for 17β-E2 pretreatment and detection in food samples, and low limit detection (2.52â¯Âµgâ¯Lâ1) and quantification (10.76â¯Âµgâ¯Lâ1) with higher recovery were obtained. Therefore, SM-MIMs may be a promising adsorbent for 17β-E2 pretreatment in food samples owing to its advantages of on/off-switchable recognition, eco-friendly elution, and efficient separation.
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Authors
Wenting Zhu, Hailong Peng, Mei Luo, Ningxiang Yu, Hua Xiong, Ronghui Wang, Yanbin Li,