Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7590482 | Food Chemistry | 2016 | 8 Pages |
Abstract
The aim of this study was to compare phenolic profile, vitamin C content, antioxidant, anti-inflammatory and cytotoxic activity of rose hips and the preserves (purée and jam) of two Rosa species: renowned Rosa canina L. and unexplored Rosa arvensis Huds. The liquid chromatography-tandem mass spectrometry analysis of 45 phenolics resulted in quantification of 14 compounds, with quercitrin, gallic and protocatechuic acids as the most dominant. High antioxidant potential of R. canina and a moderate activity of R. arvensis extracts were determined through several assays. Purée of both species and methanol extract of air-dried R. canina hips showed some anti-inflammatory (cyclooxygenase-1 and 12-lipooxygense inhibition potency) activity. Purée of R. canina exerted cytotoxic activity only against the HeLa cell line among several others (HeLa, MCF7, HT-29 and MRC-5). The presented results support traditional use of rose hips and their fruit preserves as food with health and nutritional benefits.
Keywords
COX-1TXB2HT-29PGE2AAEGAEMRC-512(S)-hydroxy-(5Z,8Z,10E,14Z)-eicosatetraenoic acid12-HETE12-HHT12-lipoxygenase12-LOXcolon adenocarcinoma cell lineReducing power assayLOQPGB2MCF7FRAPSRBMDARosa canina L.BHTDPPH2,2-diphenyl-1-picrylhydrazyl radicalLC–MS/MSgallic acid equivalentsthromboxane B2sulforhodamine Bcyclooxygenase-1Antioxidant activityCytotoxic activityAnti-inflammatory activitymalondialdehydelimit of quantificationascorbic acid equivalentsquercetin equivalentsbutylated hydroxytoluenedry weightLipid peroxidationprostaglandin B2Prostaglandin E2propyl gallateHela
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jelena D. NaÄpal, Marija M. Lesjak, Filip S. Å ibul, Goran T. AnaÄkov, Dragana D. ÄetojeviÄ-Simin, Neda M. Mimica-DukiÄ, Ivana N. Beara,