Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7590519 | Food Chemistry | 2015 | 5 Pages |
Abstract
The solubilities of bioactive compound vanillin were measured in various propane-1,2-diol + water cosolvent mixtures at T = (298-318) K and p = 0.1 MPa. The experimental solubility of crystalline vanillin was determined and correlated with calculated solubility. The results showed good correlation of experimental solubilities of crystalline vanillin with calculated ones. The mole fraction solubility of crystalline vanillin was recorded highest in pure propane-1,2-diol (7.06 Ã 10â2 at 298 K) and lowest in pure water (1.25 Ã 10â3 at 298 K) over the entire temperature range investigated. Thermodynamic behavior of vanillin in various propane-1,2-diol + water cosolvent mixtures was evaluated by Van't Hoff and Krug analysis. The results showed an endothermic, spontaneous and an entropy-driven dissolution of crystalline vanillin in all propane-1,2-diol + water cosolvent mixtures. Based on solubility data of this work, vanillin has been considered as soluble in water and freely soluble in propane-1,2-diol.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Faiyaz Shakeel, Nazrul Haq, Nasir A. Siddiqui, Fars K. Alanazi, Ibrahim A. Alsarra,