Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7595264 | Food Chemistry | 2015 | 7 Pages |
Abstract
The effects on lipid and glucose metabolism of a hazelnut skin extract (FIBEROXâ¢) administrated during 8 weeks (HFD-FBX8w group) or during the last 4 weeks of the study (HFD-FBX4w group) to Golden Syrian hamsters fed a high-fat diet (HFD) for 8 weeks were investigated. FIBEROX⢠consumption reversed the increase in total and LDL plasma cholesterol induced by the HFD feeding in both HFD-FBX groups and decreased the circulating levels of free fatty acids and triglycerides in the HFD-FBX4w animals. The higher excretion of bile acids found in the faeces of both groups of hamsters fed the FIBEROX⢠suggests that this mechanism is involved in the cholesterol-lowering effects of the extract. Furthermore, FIBEROX⢠intake sharply decreased the lithocholic/deoxycholic bile acid faecal ratio, a risk factor for colon cancer, in both HFD-FBX groups. In conclusion, the consumption of FIBEROX⢠improves different risk factors associated with cardiovascular disease and colon cancer.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Antoni Caimari, Francesc Puiggròs, Manuel Suárez, Anna Crescenti, Sirle Laos, Juan Antonio Ruiz, Virginia Alonso, Josep Moragas, Josep Maria del Bas, LluÃs Arola,