Transport across Caco-2 monolayers of peptides arising from in vitro digestion of bovine milk proteins

Article ID	Journal	Published Year	Pages	File Type
7601715	Food Chemistry	2013	10 Pages	PDF

Abstract

âº Casein and whey proteins were in vitro digested and applied to Caco-2 monolayers. âº Resistant peptides able to translocate across monolayers were characterised. âº Minor amount of supposed bioactive peptides were detected. âº After digestion milk proteins almost completely lost the IgE-binging properties. âº Î²-Lg 127-135 is a possible “immune sensitising factors” in vivo.

Keywords

Cow’s milk allergy Caco-2 cell monolayers Peptide uptake Gastrointestinal digestion Milk proteins Bioactive peptides

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

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Transport across Caco-2 monolayers of peptides arising from in vitro digestion of bovine milk proteins

Authors

Gianluca Picariello, Giuseppe Iacomino, Gianfranco Mamone, Pasquale Ferranti, Olga Fierro, Carmen Gianfrani, Aldo Di Luccia, Francesco Addeo,