Article ID Journal Published Year Pages File Type
7604320 International Journal of Mass Spectrometry 2015 10 Pages PDF
Abstract

- HILIC provides a robust and reproducible off-line LC method for 2D-LC deep proteomics workflows.
- HILIC is part-orthogonal to hSAX fractionation.
- HILIC-based workflow identified ∼81,000 peptides from >9000 proteins with an average sequence coverage of ∼26%.
- HILIC is well suited for the study of hydrophilic PTMs.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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