| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7604368 | International Journal of Mass Spectrometry | 2015 | 33 Pages |
Abstract
- UV-activation (266 nm) can homolytically cleave a disulfide bond.
- UV-activation with ECD allowed the three disulfide bonds of insulin to be cleaved.
- For proteins, combined IR/UV-activation facilitates ECD disulfide bond cleavage.
- Protein SS bonds can reform within 10-100Â ms after their UV-homolytic cleavage.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Piriya Wongkongkathep, Huilin Li, Xing Zhang, Rachel R. Ogorzalek Loo, Ryan R. Julian, Joseph A. Loo,