Study on the loss of nucleoside mono-, di- and triphosphates and phosphorylated peptides to a metal-free LC-MS hardware

Article ID	Journal	Published Year	Pages	File Type
7605982	International Journal of Mass Spectrometry	2011	8 Pages	PDF

Abstract

Nucleotides and phosphopeptides strongly interact with metal-free LC-ESI hardware. The main site of adsorption is traced back to the fused silica tubing. A solution is suggested.

Keywords

ICP PAEK Sample loss ADP AMP ATP EDTA Metal-free LOD یا Limit of detection Dimethyldichlorosilane PEEK fused silica Mass spectrometry Phosphoric acid Phosphopeptide Internal Diameter limit of detection Nucleotide inductively coupled plasma polyether ether ketone liquid chromatography