Article ID Journal Published Year Pages File Type
7607629 Journal of Chromatography A 2018 11 Pages PDF
Abstract
The pump and back pressure regulator (BPR) pressures are not necessarily good indicators of pressures or densities in the column. At high flow rates the extra-column pressure drop (ΔP) can be much larger than the column ΔP and can be unevenly distributed in front of and behind the column. In one extreme the ΔP after the column was 3 times higher (105 bar) than the actual column ΔP (32 bar).
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
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