Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7607748 | Journal of Chromatography A | 2018 | 12 Pages |
Abstract
These conditions were applied to a representative set of metabolites belonging to nucleosides, nucleotides, small organic acids, small bases, sulfated/sulfonated metabolites, poly-alcohols, lipid related substances, quaternary ammonium metabolites, phosphate-based substances, carbohydrates and amino acids. Among all these metabolites, 65% of the compounds were adequately analyzed with excellent peak shape, 23% provided distorted peak shapes, while only 12% were not detected (mostly metabolites having several phosphate or several carboxylic acid groups).
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Authors
Vincent Desfontaine, Gioacchino Luca Losacco, Yoric Gagnebin, Julian Pezzatti, William P. Farrell, VÃctor González-Ruiz, Serge Rudaz, Jean-Luc Veuthey, Davy Guillarme,