Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7608195 | Journal of Chromatography A | 2018 | 18 Pages |
Abstract
Microfabricated semi-packed gas chromatography (GC) columns coated with two kinds of mesoporous silica (MS) stationary phase have been explored and compared in this paper. The micro GC (μGC) columns are fabricated by microelectromechanical system (MEMS) technique. MSs with pore size of 2 and 5â¯nm are prepared using two different soft-templates and deposited on the inner surface of the μGC columns by dip-coating. For the first time, the influence of pore size of MS stationary phase on the separation performance in a μGC column has been investigated. As demonstrated, the mixtures of light alkanes (C1-C4) or heavy alkanes (C5-C10) can be well separated in both columns, where the separation resolution is always higher than 1.25 except for C1-C2 and C5-C6. Considering the pore size effect on the separation performance, it is shown that analytes, especially those with bigger size, display longer retention time in the column with larger pore size. For C10, the retention time in 5â¯nm-MS column is 200% longer than that in 2â¯nm-MS one.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Lei Hou, Fei Feng, Wenbin You, Pengcheng Xu, Fan Luo, Bowen Tian, Haimei Zhou, Xinxin Li,