Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7608468 | Journal of Chromatography A | 2018 | 8 Pages |
Abstract
The present study reports successful separations of enantiomers of selected chiral sulfoxides with very high separation factor in high-performance liquid chromatography by using chiral columns prepared with the chiral selector cellulose tris(4-chloro-3-methylphenylcarbamate). High separation factors were observed in polar organic, as well as in hydrocarbon-alcohol-type mobile phases. The key structural components of the solute for obtaining high chiral recognition are discussed as well as thermodynamic quantities of analyte adsorption on the chiral stationary phase were determined. Experiment aimed at the enantioselective extraction of racemates from solution are also described.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Tamar Khatiashvili, Rusudan Kakava, Iza Matarashvili, Hadi Tabani, Chiara Fanali, Alessandro Volonterio, Tivadar Farkas, Bezhan Chankvetadze,