Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7608631 | Journal of Chromatography A | 2018 | 8 Pages |
Abstract
In recent years, artificial materials with double helix structure have attracted widespread attention due to their unique properties such as the DNA like double-helicity, intrinsic chirality and diverse functional groups. Developing novel chiral stationary phases (CSPs) for capillary electrochromatography enantioseparation is of intriguing interest. Herein, a novel homochiral zeolite-like metal-organic framework (ZMOF) JLU-Liu23 with unique DNA like double-helicity structure was firstly utilized as the CSP in open tubular capillary electrochromatography (OT-CEC) for enantioseparation of chiral monoamine neurotransmitters and analogues. Owing to the unique DNA like double-helicity structure of the homochiral ZMOF JLU-Liu23, the good enantioseparation of four monoamine neurotransmitters and analogues was achieved on the prepared homochiral ZMOF JLU-Liu23 coated capillary column. The relative standard deviations (RSDs) of the analytes migration time for intra-day, inter-day and column-to-column were in the range of 0.3-0.6%, 0.8-2.2% and 3.5-6.5%, respectively.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Congjie Pan, Wenjuan Lv, Xiaoying Niu, Guoxiu Wang, Hongli Chen, Xingguo Chen,