Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7611093 | Journal of Chromatography A | 2015 | 6 Pages |
Abstract
The hyphenated technique used provided nanoparticle size-based separation, elemental detection, and composition analysis capabilities that turned out to be instrumental in order to investigate in depth the Ab-QDs bioconjugation process. Moreover, the analytical strategy here proposed allowed us not only to clearly identify the bioconjugation reaction products but also to quantify nanoparticle:antibodies bioconjugation efficiency. This is a key issue in future development of analytical and bioanalytical photoluminescent QDs applications.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Mario Menéndez-Miranda, Jorge Ruiz Encinar, José M. Costa-Fernández, Alfredo Sanz-Medel,