| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7611398 | Journal of Chromatography A | 2015 | 71 Pages |
Abstract
A definition of chromatographic orthogonality is suggested that is based on maximizing the values of OMs or OM products. This optimization criterion suggests using the product of a global metric that measures the utilization of separation space (e.g., the convex hull relative area) and a local metric that measures peak spacing (e.g., the box-counting fractal dimension). The “best” column pairs for 2D chromatography are chosen by the product of these OMs.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Mark R. Schure, Joe M. Davis,