Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7614553 | Journal of Chromatography A | 2012 | 9 Pages |
Abstract
⺠A new mode of achieving retention on a hydrophilic solid phase is described. ⺠Retention is achieved by mutual steric exclusion of polyethylene glycol. ⺠Direct chemical interaction between the target molecule and the solid phase is not required. ⺠Selectivity is dominantly a function of molecular size. ⺠The method is especially effective for purification of large proteins and viruses.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jeremy Lee, Hui Theng Gan, Sarah Maria Abdul Latiff, Cindy Chuah, Wan Yee Lee, Yuan-Sheng Yang, Bernard Loo, Say Kong Ng, Pete Gagnon,