Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7614846 | Journal of Chromatography B | 2018 | 8 Pages |
Abstract
4-n-butyl resorcinol (4-nBR) is a highly effective tyrosinase inhibitor, and can be used in cosmetic product for depigmentation purpose. Its efficacy correlates with 4-nBR that absorbed by skin. In this study, skin distribution of 4-nBR within either human or pig skin ex vivo was studied and compared by three independent laboratories. Good agreement was observed in each compartment considering usual inter-lab variability. This study supports the use of pig skin as an alternative source of skin when the availability of human skin is a limiting factor.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Yang Liu, Haiyan Ni, William Wargniez, Sébastien Grégoire, Ingrid Durand, Laurène Roussel-Berlier, Joan Eilstein, Qiang Jie, Tian Ma, Teng Shen, Yingyin Wang, Jie Qiu,