Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7615046 | Journal of Chromatography B | 2018 | 50 Pages |
Abstract
Achievements of supercritical fluid chromatography with mass spectrometric detection made in the field of forensic science during the last decade are reviewed. The main topics include analysis of traditional drugs of abuse (e.g. cannabis, methamphetamine) as well as new psychoactive substances (synthetic cannabinoids, cathinones and phenethylamines), doping agents (anabolic steroids, stimulants, diuretics, analgesics etc.) and chemical warfare agents. Control of food authenticity, detection of adulteration and identification of toxic substances in food are also pointed out. Main aspects of an analytical workflow, such as sample preparation, separation and detection are discussed. A special attention is paid to the performance characteristics and validation parameters of supercritical fluid chromatography-mass spectrometric methods in comparison with other separation techniques.
Keywords
EtAcPDAAMPSPEEtOHUHPLCCSHMTBECCHWADAESISAXMECN2-EthylpyridineFluorophenylUHPSFC2-Picolylaminei-PrOHAMY1THFSRMTHCLLEDEA1-AminoanthraceneNPsΔ9-Tetrahydrocannabinolphotodiode arrayAmphetamineEthanolEthyl acetateSolid phase extractionLiquid-liquid extractionSupported liquid extractionAcetonitrileStearic acidOleic acidMyristic acidFatty acidFood authenticityTetrahydrofurantriacylglycerolTAG یا triacylglycerols AdulterationLOD یا Limit of detectionBehdiethylaminediacylglycerolDiolchromatographic resolutionDAGcoefficient of determinationMass spectrometrylauric acidSLENew psychoactive substanceMethanolMethamphetaminemethyl tert-Butyl etherlimit of detectionDrug of abuseMeOHselected reaction monitoringHILICPalmitic acidPropan-2-olUltra-high performance supercritical fluid chromatographyUltra-high performance liquid chromatographyReversed-phase liquid chromatographyhydrophilic interaction liquid chromatographyDoping controlelectrospray ionization
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Volodymyr Pauk, Karel Lemr,