| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7618730 | Journal of Chromatography B | 2012 | 6 Pages |
Abstract
⺠G004, a novel bromine-containing hypoglycemic agent with antithrombosis effect. ⺠The detection of an interfering metabolite in the LC-MS/MS bioanalysis of G004. ⺠MS conditions were optimized to eliminate the interference from the metabolite. ⺠Metabolite-related matrix effect was evaluated by the standard addition method. ⺠Pharmacokinetics of G004 in beagle dogs was reported for the first time.
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Authors
Linlin Hu, Li Ding, Xiaobing Li, Na Zhou, Shuisheng Zhong, Guanzhong Wu, Huibin Zhang,