Article ID Journal Published Year Pages File Type
7618843 Journal of Chromatography B 2012 6 Pages PDF
Abstract
► A method to analyze NNN and its metabolites with HPLC-MS/MS was established. ► Hydroxy acid was the major metabolite of NNN in rabbit blood. ► 5′-Hydroxylation of NNN might be the main metabolic pathway of NNN in rabbit blood. ► Metabolic curves and pharmacokinetic parameters were obtained for NNN and its metabolites.
Related Topics
Physical Sciences and Engineering Chemistry Analytical Chemistry
Authors
, , , , , , ,