| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7619110 | Journal of Chromatography B | 2012 | 7 Pages |
Abstract
⺠FMOC-Cl is a suitable labeling agent for derivatization of chemicals amines or hydroxyl groups. ⺠The reagent was applied in labeling of valproate (VPA) an anticonvulsant with carboxylic acid moiety. ⺠To document reaction between FMOC-Cl and carboxylic acid moiety a LC-MS/MS method was developed. ⺠The method is simple, rapid, sensitive which needs using lower sample volume. ⺠Potential application of FMOC in assay of carboxylic acids, makes our method attractive.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bahareh Mohammadi, Mohammad Bagher Majnooni, Pyman Malek Khatabi, Ronak Jalili, Gholamreza Bahrami,