| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7619182 | Journal of Chromatography B | 2012 | 8 Pages |
Abstract
⺠Separation of HBsAg virus-like particles from yeast is achieved with a monolith. ⺠Dynamic binding capacity for VLP with untreated feed is 3-4x that of a packed bed. ⺠Confocal microscopy is used to visualise the degree and position of lipid fouling. ⺠A lipid layer is seen on the monolith even after regeneration with 30% isopropanol. ⺠Reducing the lipid in the yeast homogenate causes the capacity to increase 2.5x.
Related Topics
Physical Sciences and Engineering
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Authors
Claire S. Burden, Jing Jin, Aleš Podgornik, Daniel G. Bracewell,