| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7619201 | Journal of Chromatography B | 2012 | 8 Pages |
Abstract
⺠Development of a HPLC method for camptothecin (CPT) pharmacokinetic studies. ⺠CPT was administered in solid lipid nanoparticles to rats. ⺠Fluorescence detection allowed quantification limit value â¤0.5 ng/mL. ⺠The method was specific, accurate and precise in all biological matrices. ⺠CPT was stable after 24 h at RT or at 4 °C, or after three freeze/thaw cycles.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Susana M. Martins, Thierry Wendling, VirgÃnia M.F. Gonçalves, Bruno Sarmento, Domingos C. Ferreira,