Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7619218 | Journal of Chromatography B | 2012 | 8 Pages |
Abstract
⺠We developed and validated a novel uHPLC-MS/MS assay for the simultaneous quantification of clopidogrel and its derivatized active metabolite. ⺠Clinically relevant calibration ranges for clopidogrel (0.01-50 ng/mL) and active metabolite (0.1-150 ng/m) were used. ⺠Successfully applied to clinical phase I study using 3 subjects.
Keywords
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Cody J. Peer, Shawn D. Spencer, Dustin A.H. VanDenBerg, Michael A. Pacanowski, Richard B. Horenstein, William D. Figg,