| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7625572 | Journal of Pharmaceutical and Biomedical Analysis | 2018 | 9 Pages |
Abstract
Quality control (QC) is crucial for ensuring the safety and effectiveness of traditional Chinese medicines (TCMs). Due to extremely complicated phytochemical matrices and characteristic mode of “multi-component, multi-target, integrated adjustment”, discovering of QC markers from TCMs is a big challenge. Fingerprint-efficacy (FE) modeling method is currently proposed as an effective and reasonable attempt. This review summarizes the methodologies of FE modeling and applications in screening QC markers, meanwhile the future perspectives are also briefly discussed so as to provide inspiration and reference for follow-up study of FE relationship for TCMs.
Related Topics
Physical Sciences and Engineering
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Analytical Chemistry
Authors
Cai Zhang, Xian Zheng, Hui Ni, Ping Li, Hui-Jun Li,