Analysis of nicotine and cotinine in hair by on-line in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry as biomarkers of exposure to tobacco smoke

Article ID	Journal	Published Year	Pages	File Type
7626479	Journal of Pharmaceutical and Biomedical Analysis	2018	24 Pages	PDF

Keywords

UHP CXP DCM MRM COT LLE TMAH MIP LOQ ECD CUR ESI SPME API GC–MS LC–MS/MS In-tube solid-phase microextraction MS/MS n-Hexane internal standard Liquid–liquid extraction Acetonitrile Formic acid collision energy Solid phase microextraction Exposure biomarkers Electrochemical detection LOD یا Limit of detection Room temperature Dichloromethane World Health Organization CAD Tandem mass spectrometry headspace Limits of quantification limits of detection Hair Molecular imprinted CAN multiple reaction monitoring Nicotine Tetramethylammonium hydroxide declustering potential collision cell exit potential entrance potential NIC high performance liquid chromatography HPLC gas chromatography with mass spectrometry WHO Cotinine Collision gas curtain gas Electro spray ionization Atmospheric pressure ionization overnight

Related Topics

Physical Sciences and Engineering Chemistry Analytical Chemistry

Analysis of nicotine and cotinine in hair by on-line in-tube solid-phase microextraction coupled with liquid chromatography-tandem mass spectrometry as biomarkers of exposure to tobacco smoke

Authors

Takehito Inukai, Sanae Kaji, Hiroyuki Kataoka,