Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7626597 | Journal of Pharmaceutical and Biomedical Analysis | 2018 | 14 Pages |
Abstract
The highest radical scavenging in both ABTS and DPPH assays was noted in GPE, as well as ferric and cupric reducing abilities. However, GTE had the strongest metal chelating activity (17.44â¯Â±â¯0.51â¯mg EDTAE/g extract). GPE and GGE were more potent as acetylcholinesterases inhibitors witnessed by 2.09â¯Â±â¯0.02â¯mg GALAE/g extract and 1.59â¯Â±â¯0.09 mgGALAE/g extract, respectively. All flavonoids were found in G. glomerata for the first time. Therefore, further isolation and structural elucidation of newly described acetylated flavonoids are needed in order to determine their relevance in the beneficial properties of the plant.
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Authors
Dimitrina Zheleva-Dimitrova, Gokhan Zengin, Vessela Balabanova, Yulian Voynikov, Valentin Lozanov, Irina Lazarova, Reneta Gevrenova,