| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7626958 | Journal of Pharmaceutical and Biomedical Analysis | 2018 | 33 Pages |
Abstract
The method was applied to clinical samples from three patients treated with pazopanib to establish the metabolite profiles (semi-quantitative data) during treatment. The assessment of metabolite profiles could be useful to improve our understanding of the occurrence of adverse events and to improve pazopanib pharmacokinetic-pharmacodynamic relationships.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Marie-Noëlle Paludetto, Florent Puisset, Félicien Le Louedec, Ben Allal, Thierry Lafont, Etienne Chatelut, Cécile Arellano,