| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7628219 | Journal of Pharmaceutical and Biomedical Analysis | 2016 | 7 Pages |
Abstract
In conclusion, SR-XRF and LA-ICP-MS are suitable and highly sensitive techniques to analyze the penetration depth and distribution of Pt-based drugs after IP administration. To the best of our knowledge, this is the first experiment in which the distribution of Pt is analyzed at the cellular level after IP administration of cisplatin.
Keywords
ROISR-XRFIPCGAGIQRCRSppmECMLA-ICP-MScpsHIPECH&EPCARgbArgonbrominePrincipal component analysisCytoreductive surgeryintraperitonealMonte CarloOvarian cancerSulfurcounts per secondPhosphorusZincred green blueparts per millionMetallothioneinsinterquartile rangeCopperregion of interestManganeseprincipal componenthaematoxylin and eosinHyperthermiaPlatinumCalciumGlycosaminoglycans
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Charlotte Carlier, Brecht Laforce, Stijn J.M. Van Malderen, Félix Gremonprez, Remi Tucoulou, Julie Villanova, Olivier De Wever, Laszlo Vincze, Frank Vanhaecke, Wim Ceelen,