| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7628455 | Journal of Pharmaceutical and Biomedical Analysis | 2016 | 23 Pages |
Abstract
Liquid-liquid extraction with UPLC-MS/MS is a convenient approach to measure low levels of NNAL in urine as a marker of biological NNK exposure, which can be used to assess the effectiveness of smoking reduction harm minimisation strategies. Enzymatic hydrolysis of NNAL-glucuronide and measuring the aglycone is not recommended.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Wenying Lu, Stuart G. Ferguson, David S. Nichols, Rahul Patel, Glenn A. Jacobson,