| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629253 | Journal of Pharmaceutical and Biomedical Analysis | 2016 | 39 Pages |
Abstract
Plasma and tumor CHO-PTX levels and the radio of CHO-PTX concentration in tumor/plasma at 0.25, 3, 24, and 120 h after a single intravenous administration of CHO-PTX lipid emulsions at a dose equivalent to 20 mg/kg paclitaxel to mice with MDA-MB-231 human breast tumor xenografts. Each point represents the mean ± SD (n = 5).
Keywords
MRMULOQMQCDTXLCTHQCMTBEMCTLLELQCESILLOQMatrix effectinternal standardLiquid–liquid extractionEmulsionMedium-chain triglycerideslong-chain triglyceridesupper limit of quantificationlower limit of quantificationDocetaxelBioanalytical methodmethyl tert-Butyl ethermultiple reaction monitoringhigh quality controlquality controllow quality controlelectrospray ionization
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Xuejun Xia, Xiaowei Song, Jiaming Xu, Jiuming He, Jie Peng, Xiang Zhang, Dujia Jin, Zeper Abliz, Yuling Liu,