| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629443 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 24 Pages |
Abstract
- Forced degradation study of fingolimod was carried out as per ICH guidelines.
- The drug degraded in base hydrolysis to form three degradation products (DPs).
- DPs were characterized by LC-Q-TOF-MS/MS and NMR.
- Acetonitrile as co-solvent in stress studies reacted and formed acetylated DPs.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Prinesh N. Patel, Pradipbhai D. Kalariya, S. Gananadhamu, R. Srinivas,