Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
7629500 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 9 Pages |
Abstract
- UPLC-ESI-MS/MS method was developed for screening of inhibitors of MAO.
- 5-HT and 2-PEA were used as markers to evaluate MAO inhibitive activities of drugs.
- The assay is run within 3.5Â min with acceptable sensitivity and reproducibility.
- The obtained IC50 and Ki values were as the same as the values in previous study.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Bo Jiang, Shuping Li, Wei Liu, Yadi Yang, Wenxia Chen, Dandan He, Xuemei Cheng, Zhengtao Wang, Wansheng Chen, Changhong Wang,