| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 7629589 | Journal of Pharmaceutical and Biomedical Analysis | 2015 | 6 Pages |
Abstract
- 19 compounds were screened out as direct thrombin inhibitors.
- Three compounds were discovered to inhibit thrombin for the first time.
- Docking results gave a reasonable explanation for thrombin-ligand interaction.
- The global screening method was universal for other enzymes.
Related Topics
Physical Sciences and Engineering
Chemistry
Analytical Chemistry
Authors
Jun Lu, Hui-Peng Song, Ping Li, Ping Zhou, Xin Dong, Jun Chen,