Identification of ginsenoside markers from dry purified extract of Panax ginseng by a dereplication approach and UPLC-QTOF/MS analysis

- The dereplication approach for the rapid ID of ginsenosides in ginseng preparation was developed.
- The dereplication approach using LC/MS analysis helped the discovery of new ginsenosides.
- The metabolic markers during manufacturing process were suggested by LC/MS and multivariate analysis.
- The metabolic pathway of ginsenosides during the manufacturing process were proposed.
- This approach can be utilized as the new quality control of ginseng preparations.